µP

microPublication Biology

Laura Romanelli-Cedrez1ORCID logo, and Gustavo Salinas1,2§ORCID logo

1Worm Biology Lab, Institut Pasteur de Montevideo

2Biociencias, Universidad de la Republica, Facultad de Quimica

§Correspondence to: Gustavo Salinas (gsalin@fq.edu.uy)

Abstract

Description

Methods

Extended Data

  • Description: EC₅₀ values for three nematicidal compounds against Caenorhabditis elegans under different experimental conditions. Assays were performed either in growth medium only (no bacteria), or in the presence of Lactobacillus reuteri (grown in MRS medium) or Escherichia coli (grown in LB medium). For each bacterial condition, assays were conducted either without pre-incubation or after pre-incubating the bacteria with the compounds for 4 hours. EC₅₀ values are expressed as mean ± SEM. n: number of biological replicates of dose-response curves. Medians were compared across medium control and bacterial groups using the Kruskal-Wallis test. No drug showed a statistically significant difference (P > 0.05).. Resource Type: Dataset. DOI: 10.22002/60xz4-tvm54
  • Description: Statistical analysis of the motility curves C to H to address one question of the reviewer.. Resource Type: Dataset. DOI: 10.22002/e50cj-bam56
  • Description: This Figure shows the statistical analysis for all the replicas of the motility curves E, G and H to address one question of the reviewer.. Resource Type: Dataset. DOI: 10.22002/g92hy-tkm09

Acknowledgements

Conflicts of Interest

Funding

Author Contributions

  • Laura Romanelli-Cedrez: Investigation, Methodology, Validation, Writing - original draft, Writing - review & editing
  • Gustavo Salinas: Conceptualization, Investigation, Methodology, Writing - original draft, Writing - review & editing

Reviewed By

Anonymous

Nomenclature Validated By

Anonymous

Database Reference ID: WBPaper00069990

History

  • Received: 1/26/2026
  • Revision Received: 2/3/2026
  • Accepted: 7/18/2026
  • Published Online: 7/20/2026

References

Copyright

© 2026 by the authors. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International (CC BY 4.0) License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Citation

microPublication Biology is published by

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The microPublication project is supported by

The National Institute of Health -- Grant #: 1U01LM012672-01

microPublication Biology:ISSN: 2578-9430